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chorismic acid : ウィキペディア英語版
chorismic acid

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Chorismic acid, more commonly known as its anionic form chorismate, is an important biochemical intermediate in plants and microorganisms. It is a precursor for:
* The aromatic amino acids phenylalanine, tryptophan, and tyrosine
* Indole, indole derivatives and tryptophan
* 2,3-Dihydroxybenzoic acid (DHB) used for enterobactin biosynthesis
* The plant hormone salicylic acid
* Many alkaloids and other aromatic metabolites.
*The folate precursor ''para''-aminobenzoate (pABA)
* The biosynthesis of Vitamin K and folate in plants and microorganisms.
The name chorismic acid derives from a classical Greek word, ''χωρίζω'' meaning "to separate", because the compound plays a role as a branch-point in aromatic amino acid biosynthesis.
== Biosynthesis ==
Shikimate → shikimate-3-phosphate → 5-enolpyruvylshikimate-3-phosphate (5-O-(1-carboxyvinyl)-3-phosphoshikimate)
:
Chorismate synthase is an enzyme that catalyzes the final chemical reaction 5-O-(1-carboxyvinyl)-3-phosphoshikimate → chorismate + phosphate.
:

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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